Microfluidics for Biotechnology
Jean Berthier and Pascal Silberzan
The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this cutting-edge resource offers keen insight into this burgeoning field. Supported with over 800 equations and more than 340 illustrations, the book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. You gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and discrete Monte-Carlo methods.
This unique volume describes the transport and dispersion of biochemical species and particles. You learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps you master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.
About the Authors
Jean Berthier is a scientist at CEA/LETI and teaches at the University of Grenoble. He holds a masters degree in mathematics from the University of Grenoble and both an engineers and masters degree in fluid mechanics from the Institut National Polytechnique.
Pascal Silberzan is a senior scientist at the Physico-Chimie Curie Laboratory, a joint laboratory of the Centre National of the Recherche Scientifique and the Institut Curie in Paris. He received his Ph.D. from the College of France and the University Paris 6.