Finite element analysis approach for optimization of enzyme activity for enzymatic bio-fuel cell

C. Wang[1], Y. Song[1], Y. Parikh[1], and J.H. Yang[1]
[1]Department of Mechanical & Materials Science Engineering, Florida International University, Miami, Florida, USA
Published in 2009

Enzymatic biofuel cells (EBFCs) are miniature implantable power sources, which use enzymes as catalysts to perform redox reaction with biological fuels such as glucose. In this study, we focused on a three dimensional EBFC chip with highly dense micro-electrode arrays, fabricated by carbon-micro-electro-mechanical-system (C-MEMS) techniques. Glucose oxidase (GOx) is immobilized on anodes for the oxidation of glucose from blood, and laccase is immobilized on cathodes for the reduction of dissolved oxygen in the body. We mainly focus on two critical parameters related to the biofuel cells efficiency: one is the direct electron transfer between enzyme and electrode, and another one is how to generate maximum current density or power density.

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