See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties new

K. Cluff[1], H. Mehraein[1], G. Jayakumar[2]
[1]Bioengineering, Wichita State University, Wichita, KS, USA
[2]Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical ... Read More

Feed-forward/Feed-backward Mechanical Amplification in the Mouse Cochlea

J. Soons[1,2], C. Steele[2], S. Puria[2]
[1]Lab of Biomedical physics, University of Antwerp, Antwerp, Belgium
[2]Department of Mechanical Engineering, Stanford University, Stanford, USA

Sound vibrations are collected from the external environment by the eardrum and are guided to the basilar membrane in the cochlea. Pressure differences in the two scalae of the cochlea result in a traveling wave on the basilar membrane. The tiny displacements are detected by the ... Read More

Hemodynamic Simulations of Implanted Multilayer Flow Modulator

A.B. Boubker[1], A. Restante[1]
[1]CARDIATIS, Isnes, Belgium

Ruptured aortic aneurysm is one of the commonest cause of mortality in developed countries. To avoid it interventional repair is an effective treatment. In the recent years the development of new therapies, such as stent implantations, allows to perform this treatment more and more ... Read More

FEM Simulation of Magnetically Triggered Hydrogel Micro Particles as Advanced Drug Carriers new

O. Yassine[1], M. Kavaldzhiev[1], J. Kosel[1], Q. Li[1], A. Alfadhel[1], A. Zaher[1]
[1]Electrical Engineering Division, CEMSE Group, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia

Thermally responsive microgel Poly (N-isopropylacrylamide), particles are embedded with iron oxide nanobeads creating magneto-thermally responsive microparticles (MTMs). The magnetic losses in the nanobeads activate the PNIPAM by heating it up to its lower critical solution temperature ... Read More

Development of a Microfluidic-Based Electrochemical Cell for Analyzing Bacterial Biofilms

I. Claydon [1], J. Turner [1], B. Sammakia [1],
[1] Binghamton University, Binghamton, NY, USA

The ubiquitous nature of biofilms has led to a growing need to be able to detect, control, and maintain or remove them. Therefore a robust testing platform that allows for multiple analytical techniques is required to better understand their multitude of properties. The development of ... Read More

Influence of Non-Newtonian Blood Viscosity on Wall Pressure in Right Coronary Arteries with Serial Stenoses

B. Liu [1]
[1] Monmouth University, West Long Branch, NJ, USA

Three dimensional mathematical models are developed to simulate the blood flows in patient specific right coronary arteries with two stenoses. Simulations are carried out with various flow parameters under physiological conditions. Both Newtonian and non-Newtonian blood viscosity models ... Read More

A Heat Transfer Analysis of the Cochlea During Magnetically-guided Cochlear Implant Surgery

F. Esmailie [1], M. Francoeur [1], T. A. Ameel [1], ,
[1] Department of Mechanical Engineering, University of Utah, Salt Lake City, UT, USA

Approximately 450,000 people worldwide suffering from hearing problems use cochlear implants (, June 12, 2018). Manual insertion of the cochlear implant during surgery can potentially damage the delicate tissues within ... Read More

Optimal PDE Control Using COMSOL Multiphysics

I. Neitzel[1], U. Prüfert[2], and T. Slawig[3]

[1]Technische Universität Berlin / SPP 1253
[2]Technische Universität Berlin / Matheon
[3]Excellence Cluster The Future Ocean, Algorithmic Optimal Control - Oceanic CO2-Uptake/SPP 1253

An optimal control problem (OCP) is studied to a PDE of elliptic type as well as state constraints. The resulting optimality system contains two PDEs, one algebraic equation and the so called complementary slackness conditions, i.e. dual products between function spaces. At this point, ... Read More

Numerical Simulations Demonstrate Safe Vitrification and Warming of Embryos Using the Rapid-i™ Device

B.O.J. Johansson[1][2], Y.A. Tarakanov[1], H.J. Lehmann[2], and S.P. Apell[1]

[1]Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden
[2]Vitrolife Sweden AB, Västra Frölunda, Sweden

During cryopreservation of human embryos, ice crystal formation in the embryos or in surrounding media may cause cryodamage to them and can be lethal. A strategy to avoid this is the vitrification procedure when the embryo and the surrounding medium undergo the transition to glassy state ... Read More

Investigation Of Bone Marrow Stem Cells In The Bone Marrow Niche In An In Vitro System

P. Lezuo, M. Stoddart, and M. Alini
AO Research Institute, Davos, Grison, Switzerland

We aim to develop an in vitro culture system to mimic the human bone marrow stem cell niche in an artificial perfusion bioreactor environment to culture human adult stem cells. State of the art human bone marrow stem cell research shows that even smallest changes in the physical, thermo ... Read More