See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2019 Collection
Bioscience and Bioengineeringx

Simulating Hodgkin-Huxley-like Excitation using Comsol Multiphysics

J. Martinek[1,2], Stickler[2] , Reichel[1], and Rattay[2]
[1]Department of Biomedical Engineering and Environmental Management, University of Applied Sciences Technikum Wien, Vienna, Austria
[2]Institute for Analysis and Scientific Computing, Vienna University of Technology, Austria

Most simulations concerning electrical activation of human muscles are based on the modeling approach of Hodgkin and Huxley. Calculating the response of a muscle or nerve fiber membrane to an applied electrical field, needs to consider the “macroscopic”, extracellular potential ... Read More

Modeling of snRNP Motion in the Nucleoplasm

M. Blaziková[1], J. Malínský[2], D. Stanek[3], and P. Herman[1]
[1]Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
[2]Institute of Experimental Medicine, Prague, Czech Republic
[3]Institute of Molecular Genetics, Prague, Czech Republic

Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the ... Read More

Heat and Mass Transfer in Convective Drying Processes

C. Gavrila[1], A. Ghiaus[1], and I. Gruia[2]
[1]Technical University of Civil Engineering Bucharest, Faculty of Building Services, Bucharest, Romania
[2]University of Bucharest, Faculty of Physics, Bucharest, Romania

A dynamic mathematical model, based on physical and transport properties and mass and energy balances, was developed for the simulation of unsteady convective drying of agricultural products (fruits and vegetables) in static bed conditions. The model utilizes water sorption isotherm ... Read More

Validation of Measurement Strategies and Anisotropic Models Used in Electrical Reconstructions

R. Sadleir
Department of Biomedical Engineering, University of Florida, Gainesville, FL, USA

We are developing approximations of electrically anisotropic materials for use in novel imaging methods. Our modeling work in COMSOL comprises comparisons of anisotropic and layered models in terms of electrical conductivities measured using different strategies. We tested solution ... Read More

Image Based-Mesh Generation for Realistic Simulation of theTranscranial Current Stimulation

R. Said[1], R. Cotton[1], P. Young[1], A. Datta[2], M. Elwassif[2] , and M. Bikson[2]
[1] Simpleware Ltd, Exeter, Devon, UK
[2] Department of Biomedical Eng., The City College of New York, New York, NY, USA

This paper will discuss the comprehensive solution adopted for converting the 3D digital/medical images directly into the computational model. The workflow using Simpleware Software – ScanIP and + ScanFE – will be illustrated including the option for directly exporting fully compatible ... Read More

Solid Food Pasteurization by means of Ohmic Heating: Influence of Process Parameters

M. Zell[1], D. Cronin[1], D. Morgan[1], F. Marra[2], and J. Lyng[1]
[1]School of Agriculture, Food Science and Veterinary Medicine, Agriculture and Food Science Centre, College of Life Sciences, UCD Dublin, Ireland
[2]Dipartimento di Ingegneria Chimica e Alimentare, Università degli Studi di Salerno, Italy

Pasteurization of solid food undergoing ohmic heating has been analyzed using COMSOL Multiphysics on the basis of a previously validated multiphysics model. The simulation of pasteurization by ohmic heating involves simultaneous solution electrical potential within the food, heat ... Read More

Image Based Mesh Generation for Realistic Simulation of the Transcranial Current Stimulation

R. Said[1], R. Cotton[1], P. Young[1], A. Datta[2] , M. Elwassif[2], and M. Bikson[2]
[1]Simpleware Ltd, Exeter, UK
[2]Department of Biomedical Eng, The City College of New York, USA

Electrical stimulation of the brain involves the application of currents delivered through scalp electrodes to modulate brain activity, known as Transcranial Current Stimulation (TCS). A critical factor for TCS efficacy and safety is the “spatial focality” of induced neuronal modulation. ... Read More

Using COMSOL Multiphysics for Modeling of Musculoskeletal Biomechanics

R. L. Spilker
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, New York, USA

In this presentation, we study the modeling of physiology and muscoskeletal biomechanics using COMSOL. The outline for the presentation is in particular: * Why is COMSOL particularly powerful for modeling physiology? * Modeling soft tissues like cartilage * Optimization to determine ... Read More

Analysis of 3D Biocompatible Additive Structure Using COMSOL Multiphysics® Software new

E. Lacatus[1], M. A. Sopronyi[2], G. C. Alecu[1], A. Tudor[1]
[1]Polytechnic University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

For biocompatible prosthetics, from dental implants up to bone parts, manufacturers have to find the best way to correlate process parameters and the material properties as to meet the unique needs of individuals. Additive manufacturing techniques aim at creating complex biocompatible ... Read More

On the Influence of Cancellous Bone Structure upon the Electric Field Distribution of Electrostimulative Implants new

U. Zimmermann[1], R.Bader[2], U. van Rienen[1]
[1]Institute of General Electrical Engineering, University of Rostock, Rostock, Germany
[2]Department of Orthopaedics, University Medicine Rostock, Rostock, Germany

Since the 1980s, the accelerating effect of electromagnetic fields on bone regeneration is used to treat complicated fractures and bone diseases. At the University of Rostock, an electrostimulative hip revision system is developed, basing on the method of Kraus-Lechner. This method ... Read More