See How Multiphysics Simulation Is Used in Research and Development

Engineers, researchers, and scientists across industries use multiphysics simulation to research and develop innovative product designs and processes. Find inspiration in technical papers and presentations they have presented at the COMSOL Conference. Browse the selection below or use the Quick Search tool to find a specific presentation or filter by application area.
View the COMSOL Conference 2018 Collection
Bioscience and Bioengineeringx

Wireless RF Digital System for Mouth-Embedded Multi-Sensor Communication

I.M. Abdel-Motaleb[1], J. Lavrencik [1]
[1]Department of Electrical Engineering, Northern Illinois University, DeKalb, IL, USA

There is urgent need to monitor dental and oral diseases, such as tooth decay, gum diseases, and teeth grinding. Such monitoring can be achieved by embedding sensors in the mouth. This technique faces some difficulties. The first is how the power needed for the operation of the sensors ... Read More

Simulating Thermotherapeutic Response Induced by Thermal Padding for Treating Acute Injuries

J. Kantor[1], Y. Feng[1], C. Acosta[1], E. Massingill[1]
[1]University of Texas at San Antonio, San Antonio, TX, USA

Cryotherapy and thermotherapy are common methods of treatment for acute injuries ranging from ankle sprains to complex surgery. The idea behind such treatment is that a change in temperature will reduce pain and constrict fluctuations in blood flow at the targeted area. The purpose of ... Read More

Simulating Organogenesis in COMSOL: Towards Efficient 3D Simulations of Organogenesis

D. Barac [1], Z. Karimadini [1], R. Croce [1], D. Iber [1]
[1] Department of Biosystems Science and Engineering (D-BSSE), ETH Zurich, Basel, Switzerland

One of the major challenges in biology concerns the integration of data across length and time scales into a consistent framework: how do macroscopic properties and functionalities arise from the molecular regulatory networks ­ and how do they evolve? A deeper understanding of ... Read More

Theoretical and Experimental Validation of Micro Hot Embossing on Polymeric Substrates

F. Lai [1], N. K. Shivaprakash [1], J. Zhang [1], A. Panwar [1], J. Mead [1], C. Barry [1], Q. Truong [2],
[1] University of Massachusetts Lowell, Lowell, MA, USA
[2] US Army Natick Soldier Research, Development and Engineering Center, Natick, MA, USA

Micro hot embossing on a large area polymeric substrates using roll-to-roll (R2R) mode has been considered as one of the most promising technologies that can offer continuous fabrication of large area polymeric substrates. Besides continuous operation, roll-to-roll (R2R) process offers ... Read More

Computational Modeling of Electrode with Saline Irrigation for Radiofrequency Cardiac Ablation

J. H. Moon [1], J. W. Ahn [1], Y. J. Kim [1], S. A. Lee [1], H. C. Jung [1], S. H. Lee [1],
[1] Osong medical innovation foundation, medical device development center, Cheongju-Si, South Korea

Radiofrequency catheter ablation is the interventional therapy that be employed to eliminate cardiac tissue caused by arrhythmias. During radiofrequency catheter ablation, the formation of thrombus can occur at electrode tip if the temperature of interface between electrode tip and ... Read More

Temperature Excursions at the Pulp-Dentin Junction during the Curing of Light-Activated Dental Restorations

M. Jakubinek[1,2], C. Neill[1], C. Felix[3], R. Price[2,3], M. White[1,2]

[1]Departments of Chemistry and Physics, Dalhousie University, Halifax, NS, Canada
[2]Institute for Research in Materials, Dalhousie University, Halifax, NS, Canada
[3]Department of Dental Clinical Sciences, Dalhousie University, Halifax, NS, Canada

Heat produced during the curing of light-activated dental restorations could damage the dental pulp. Given the prevalence of composite restorations and the importance of avoiding injury to the pulp, efforts should be made to minimize the temperature increase that occurs at the pulp ... Read More

A Virtual Pharmacokinetic Model Of A Human Eye

L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland

Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, ... Read More

COMSOL Multiphysics® Model of Canine Elbow for Use in Investigating Medial Coronoid Disease

K. A. Bodnyk[1], G. J. Noble[1], N. Fitzpatrick[2], M. J. Allen[3], K. Stephenoff[1], R. T. Hart[1]
[1]Department of Biomedical Engineering, The Ohio State University, Columbus, OH, USA
[2]Fitzpatrick Referrals, Godalming, Surrey, United Kingdom
[3]Department of Veterinary Medicine, The Ohio State University, Columbus, OH, USA

The elbow joint in dogs constitutes a complex interaction of three bones, the humerus, radius and ulna. Medial coronoid disease (MCD) is a common cause of lameness in dogs, i.e. fracturing of the most prominent portion of the ulnar joint surface driven in flexion and in pivot against ... Read More

Numerical Model Simulation of Impedance Based Control for RF Ablation Using Isolator Synergy Clamp

M. Etheridge [1], R. Lopusnik [1], A. Cates [1],
[1] AtriCure, Inc., Minnetonka, MN, USA

Thermal ablation is rapidly becoming a standard of care for the treatment of atrial fibrillation (AF), a cardiac disorder characterized by irregular heart rhythm and estimated to impact more than 33 million people worldwide (Chugh et al. Circulation (2013)). AtriCure is a company that ... Read More

Kinetics of Zebrafish Dorsoventral Patterning

B. Jordan, and P. Müller
Harvard University
Cambridge, MA

The specification of cell types and morphogenesis of many biological systems are regulated by the concentrations of signalling molecules. Many systems employ a pair of secreted short-range activators and long-range inhibitors, and these are widely used to generate complex patterns during ... Read More